Do you have your own email server? Are your messages disappearing into the ether when you try to send something to Hotmail, GMail or Yahoo Mail? Sure, we can get around this problem by replying to an email sent from these online email providers, but it's quite frustrating that we can't just make a fresh email and send it off without the message being marked as spam and deleted before the intended recipient can even read the message.
I recently had this problem when sending messages to Hotmail and GMail and, after a quick questionnaire and DNS modification, I was back in business sending messages to my friends all over the world.
How did I do this? By registering with Microsoft's SenderID program.